The Skin Wellness Center has been proud to offer the non-surgical, gold-standard treatment for non-melanoma skin cancer since April of 2019.

If you suspect that you have skin cancer or have recently been diagnosed and were told you need treatment, schedule an appointment with us today.


We offer GentleCure (Image-Guided SRT)—the surgery-free, gold-standard treatment for skin cancer. On your first visit, we will review your pathology report, discuss your treatment goals, and work with you to determine the treatment option that best meets your needs.

Want to cure your skin cancer without surgery?

GentleCure is a gentle, surgery-free treatment that is safe and has a 99%+ cure rate in basal and squamous cell skin


Treatment is done right in the dermatology office over the course of a few weeks using an advanced Image-
Guided SRT machine.


It is the only skin cancer treatment with ultra-sound imaging that lets you see the cancer  on the screen and review the progress made throughout the course of treatment until there are no visible signs of cancer.

See what to expect with treatment

At each treatment session, you will sit in a chair and ultrasound gel will be applied to the site of the cancer. Using an imaging wand, we will look at a detailed image of your cancer on screen. You can see the image yourself from the comfort of the chair. We will use that image to measure the size and shape of the tumor, calculate the precise dose of treatment, and define the treatment area.

Once the imaging is complete, the arm of the device will be placed over the treatment site and the exact dose of X-ray energy will be used to treat the cancer site without harming the healthy tissue around it.

Each treatment session takes about 15 minutes from the time you walk in the door to when you leave the office. You will come back several times a week for short treatment sessions, and in 4-to-7 weeks, treatment will be complete. 

Watch GentleCure's Short Video:

More than 66,000 patients have been successfully treated with GentleCure (Image-Guided SRT)

When Dr. Keating was diagnosed with basal cell cancer on his nose, he was scared. After discussing treatment options with his dermatologist, he chose surgery-free GentleCure (Image-Guided SRT).


In this video, Dr. Keating shares why he chose GentleCure (Image-Guided SRT) and what that experience was like for him.


Visit Stories to hear more patient stories.

GentleCure (Image-Guided SRT) has a proven track record that is backed by science and clinical research

At The Skin Wellness Center, our team of dermatologists reviewed the published research and here is what we found:

Clinically Proven

Yu L, et al. Oncol Ther. 2021;9(1):153-166.
Retrospective chart review evaluating LC rates of 1632 patients with 2917 stage 0-II carcinomas

  • In 2021, chart reviews were conducted for 1632 patients who had Image-Guided SRT to treat one or more early-stage basal or squamous cell skin cancers. Of those patients, 2917 skin cancers in total were treated. The results showed a 99.3% cure rate with Image-Guided SRT, which we believe to be equal to or better than Mohs surgery.


  • In 2022 and 2023, additional studies were published that showed the efficacy and safety of Image-Guided SRT to be superior to non-image-guided forms of radiation therapy across skin cancer types—confirming its use as a first-line treatment for basal and squamous cell skin cancers. This means doctors and patients should give equal consideration to Mohs surgery and surgery-free Image-Guided SRT as standards of care.

Why we choose to offer GentleCure (Image-Guided SRT)

There are several different radiation-based treatments available for skin cancer. But the safety, cure rates, and cosmetic outcomes vary based on the treatment technology and clinical protocols used. We chose GentleCure (Image-Guided SRT) because it is the only skin cancer treatment with advanced imaging that lets us see and measure the cancer and adapt the dose to precisely what you need at each stage of treatment. It has also been shown to be the safest and most effective of all radiation-based treatments for skin cancer with superior cosmetic results.


If you are considering radiation therapy to treat your skin cancer, make sure you are getting GentleCure (Image- Guided SRT) with adaptive radiotherapy protocols. It’s the safe, effective, and gentle way to treat skin cancer using the most advance treatment technology available today.

Treatment Results - Seeing is Believing!

No two cases of skin cancer are the same, so treatment results may vary from patient to patient. But the pictures below are typical of the results seen by patients who have received GentleCure (Image-Guided SRT).


Before Treatment

Patient with basal cell skin cancer on the top of the ear before
treatment with GentleCure (Image-Guided SRT). You can see the
cancer on the skin. The ultrasound image clearly defines the skin
cancer under the skin, indicating the full depth, width, and breadth
of the cancer.



About half way through treatment with GentleCure (Image-Guided
SRT), you can see the cancer reducing in size on the outside of the
skin. The ultrasound image shows that the cancer under the skin
has also been reduced.



At the two-week follow-up visit after treatment was completed, the
outside of the ear shows no signs of cancer. The ultrasound image
shows that GentleCure (Image-Guided SRT) continued to eliminate
the cancer. At the 30-week follow-up appointment, the ultrasound
image showed no signs of cancer.

GentleCure (Image-Guided SRT) is covered by Medicare and most health insurance plans

With most insurance plans, you may have to pay some out-of-pocket cost. That cost will depend on your specific health plan coverage and co-pay policy. Before you commit to a treatment option, we will work with your insurance plan to determine the potential cost to you, so you can make an informed treatment decision. If you are worried about affording treatment, let us know and we can discuss our financial assistance options.

Side effects and cosmetic results

When X-ray energy is used to kill cancer cells, your body will replace the dead cancer cells with healthy tissue over
time. There is no surgical scarring and no need for reconstructive surgery. There is, however, a small risk of skin
atrophy (thinning of the skin) and pigment changes (changes in the color of the skin) at the treatment site. Other
potential side effects may include skin inflammation with redness and swelling at the treatment site. Topical creams or
ointments can be used over the course of treatment to minimize these side effects, and the side effects usually go
away 2-to 6-weeks after treatment is complete.


There is also a risk of alopecia (hair loss) in the treated area only. In the 7 years that patients have been receiving GentleCure (Image-Guided SRT), there have been NO reported cases of secondary skin cancers occuring as a result of treatment.

The skin cancer treatment team at The Skin Wellness Center

Dr. Meredith Overholt, MD, FAAD

Dr. Overholt is one of the founding partners of The Skin Wellness Center. She is board-certified in dermatology and is a fellow of the American Academy of Dermatology. She received her medical degree from Baylor College of Medicine, where she also completed her residency in dermatology.


Dr. Overholt previously practiced with Knoxville’s Allergy, Asthma, and Sinus Center. She has a passion for educating her patients about diseases of the skin and ways to protect it.


Dr. Overholt recently surpassed a career milestone: 30+ years practicing in dermatology. She is also a former member of the KAM Executive board, current member of Cokesbury UMC and a Board of Ambassadors member for the American Cancer Society.

Dr. Kimberly Grande, MD, FAAD

Dr. Grande is one of the founding partners of The Skin Wellness Center. She is board-certified in dermatology and is a fellow of the American Academy of Dermatology.

She received her medical degree from the University of Nebraska where she was an Alpha Omega Alpha, however prior to training in dermatology, she completed 2 years of Internal Medicine training in Savannah, GA. She completed her residency in dermatology at Baylor College of Medicine in Houston where she met Dr. Overholt. She worked for 2 years in Houston prior to moving to Knoxville to help found The Skin Wellness Center.

The Skin Wellness Center is proud to offer the non-surgical, gold-standard treatment for non-melanoma skin cancer.

GentleCure (Image-Guided SRT) is a safe and effective, surgery-free treatment for nonmelanoma skin cancers. It
is the only skin cancer treatment that is done right in the dermatology office. GentleCure (Image-Guided SRT) is covered by many health insurance plans. Best of all, GentleCure (Image-Guided SRT) is a clinically appropriate treatment option for the majority of people diagnosed with basal cell, squamous cell, and other types of skin cancer.

When it comes to skin cancer treatment, you deserve options. We are here to help.

Appointments are available.


If you have been diagnosed with skin cancer and told you need Mohs surgery, or you are concerned that you may have skin cancer and need treatment, give us a call or contact us online today.

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